According to statistics, there are more than 2,000 veterinary drug production enterprises in China. There are about 2,000 kinds of veterinary drugs produced, and the annual output value has exceeded 15 billion yuan. There are more than 50,000 operating companies in China and annual sales are about 17 billion yuan. . The main dosage forms are only water injections, tablets and injections, and the proportion of raw material medicines is less than 5%. There is a lack of pouring agents, sustained release agents, aerosols, etc. for the prevention and treatment of group diseases that are needed by the market. The production environment, equipment and processes of most production plants are simple and backward, and the production scale is small. Veterinary drug research and development innovation capacity is weak, the number of new drugs is small, and the product technology content is low. The Ministry of Agriculture has limited the deadline for the end of 2005 to meet the GMP requirements for veterinary drug manufacturers. This indicates that the overall level of veterinary drug production will be improved, competition for survival of the fittest will be more intense, and it will be conducive to the development and application of new technologies, new processes and new products. Spray drying is one of them.
Spray drying is a method of fluidization technology used to dry liquid materials. Because it is instant drying, especially for heat-sensitive materials, the resulting product is of good quality, maintains the original color and fragrance, and is easily dissolved. Studies using spray-drying to prepare microcapsules are under way. They are suspended in a solution of a cloth material and sprayed into a hot air stream by a centrifugal atomizer. The resulting product is a microcapsule made from a cloth core material. The microcapsule powder can be used for direct compression, capsules, syrups or suspensions.
Freeze-drying is a method in which the liquid material to be dried is frozen into a solid, and the sublimation performance of ice is utilized under low-temperature decompression conditions to dehydrate the material at a low temperature to achieve drying. Because the material is dried under high vacuum and low temperature conditions, it is particularly suitable for the drying of certain extremely non-heat-resistant substances. The product obtained by spray lyophilization is small in size, fast in drying, short in time, uniform in flow, good in fluidity, and has good instant solubility.
A spray dryer is a device that can perform both drying and pelletizing. According to the technological requirements, the pressure, flow rate, and size of the orifice can be adjusted. The desired size ratio of spherical particles is obtained.
The working process of the spray dryer is as follows: the feed liquid is pumped through the diaphragm pump at a high pressure, sprays droplets of mist, and then flows down in parallel with the hot air. Most of the particles are collected at the bottom of the bottom of the column and the exhaust gas and its tiny powder are separated by cyclones. The device is separated and the exhaust gas is discharged by the exhaust fan. The powder is collected by the powder collection cylinder located under the cyclone separator. The outlet of the fan can also be equipped with a secondary dust removal device with a recovery rate of 96%-98%.
The material of the tower body, pipelines, and separators that are in contact with the material of this unit is made of SUS304. There is a thermal insulation layer between the inside of the tower body and the shell, and the filling material is rock wool. The tower body is provided with an observation door, a sight glass, a light source and a control instrument, which are controlled and displayed by the electrical control console.
The unit heat source uses steam heaters, electric heaters or other types, with the advantages of convenient operation, fast start-up, compact mechanism, and clean hot air. In addition, the electric control cabinet is equipped with a heat source control and adjustment device so that the temperature of the inlet is adjusted. The factory can provide different heating methods according to the actual needs of users.
Features of spray dryer equipment ※ The drying speed is fast, and the surface area of ​​the material liquid is greatly increased after atomization. In hot air flow, 95-98% of water can be evaporated instantaneously, and the drying time only needs ten seconds to several tens of seconds. It is especially suitable for the drying of heat sensitive materials.
※ The product obtained is spherical particles, uniform particle size, good fluidity, good solubility, high product purity, and good quality.
※ The use of a wide range, according to the characteristics of the material, can be used for hot air drying, can also use cold air granulation, the adaptability of the material.
※ The operation is simple and stable, the control is convenient, and it is easy to realize automatic operation.
Spray Dryer Scope of Application Chemicals: organic catalysts, resins, synthetic detergents, oils, thiamines, dyes, dye intermediates, silica, graphite, ammonium phosphate and so on.
Foods: Amino acids and their analogues, seasonings, proteins, starches, dairy products, coffee extracts, fishmeal, meat extract, etc.
Pharmaceuticals: proprietary Chinese medicines, pesticides, antibiotics, and pharmaceutical medicines.
Ceramics: Magnesia, china clay, various metal oxides, dolomite, etc.
Spray granulation: various fertilizers, alumina, ceramic powder, pharmaceuticals, heavy metal superhard steel, chemical fertilizers, granular detergents, proprietary Chinese medicines, etc.
There are many problems in the recovery of copper chips directly into the furnace, the recycling of copper brass chips reduces the production cost of foundry enterprises and greatly improves the market competitiveness of the enterprises. The copper scraps are small, loose, directly into the furnace will be seriously blocked, the material block clearance is the furnace gas rising channel, directly affect the smelting process, the loose steel scrap without pressing, extremely easy to float on the furnace lining, corrosion lining, and large loss of raw materials will cause low molten iron rate.
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